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ZEPOSIA: An Oral Lymphocyte Migration Blocker in UC1-4

Highly selective S1P modulator (for receptors 1 & 5) that blocks the capacity of inflammation-causing lymphocites from reaching the inflamed colon1,5-7

ZEPOSIA UC Mechanism of Action
ZEPOSIA UC Mechanism of Action

Small molecules, like ZEPOSIA, may lack immunogenicity
and may not develop antidrug antibodies1,9,10

Artist rendering for illustrative purposes.

The mechanism by which ZEPOSIA exerts therapeutic effect is unknown, but may involve reduction of lymphocyte mitigation into the intestine.1

ZEPOSIA has minimal or no activity on S1P receptors 2-4.1

S1P=sphingosine 1-phosphate; UC=ulcerative colitis.

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