ZEPOSIA blocks the capacity of lymphocytes to egress from lymph nodes, reducing the number of lymphocytes in peripheral blood.1
ZEPOSIA blocks the capacity of lymphocytes to egress from lymph nodes, reducing the number of lymphocytes in peripheral blood.1
The mechanism by which ZEPOSIA exerts therapeutic effects in MS is unknown but may involve the reduction of lymphocyte migration into the central nervous system.1
Vascular endothelial, smooth muscle cells4,6
Cardiac myocytes5
Ozanimod is an S1P receptor modulator that binds with a high affinity to S1P receptors 1 and 5 and has little activity on other S1P receptors (S1P2, S1P3, and S1P4)1,8
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