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Eligible patients enrolled in ZEPOSIA 360 Support, who have been cleared to begin treatment, and who have not received a sample from their provider, will be provided a starter kit that includes a 7-day starter pack and a 30-day supply of ZEPOSIA.
ZEPOSIA® Starter Pack ZEPOSIA® Pamphlet
ZEPOSIA® Starter Pack
ZEPOSIA 360 Support Helps Support Your Patients Every Step of the Way
Get your patients started on ZEPOSIA
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BMS Esign enables your patients to electronically sign through www.BMSesign.com

BMS eSign
Did your patient forget to sign the ZEPOSIA Start Form? Send them a link to the form below to sign electronically via CoverMyMeds.
Get the resources you and your patients need

From helpful tools and support to get them started on ZEPOSIA to additional help for your office.

ZEPOSIA 360 Support
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ZEPOSIA Starter Kit
New patients enrolled in ZEPOSIA 360 Support may be eligible for a free 28-dose Starter Kit. Please see additional eligibility requirements and terms and conditions
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Access Support
The Covermymeds Logo portal serves as a central location to manage and track your patients' access to ZEPOSIA. Access support through CoverMyMeds includes:
  • Prior authorization and appeals support
  • Digital start form for enrollment online
  • Benefits verification with electronic tracking of your patients’ benefit status
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Local, Dedicated Support
Local, dedicated support through an Access and Reimbursement Manager (ARM) team, along with dedicated ZEPOSIA Support Coordinatorsa available for your patients

Support Coordinators can provide general information about ZEPOSIA 360 Support but cannot provide medical advice.

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Pre-Initiation Support
Assistance with baseline assessments—including in-home services with scheduling and appointments available 7 days a week nationwide for eligible, commercially insured patients
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24-Month Bridge Program
The ZEPOSIA Bridge Program may provide help for eligible, commercially insured patients who are experiencing a delay in obtaining coverage or have been denied coverage
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Co-Pay Assistance Program: May Pay as Little as $0
Helps patients with co-pay costs, including prescription and medical benefits where eligible commercially insured patients may pay as little as $0 for their prescription and can be reimbursed for out-of-pocket costs associated with pre-initiation testing
Please click here to view full Terms and Conditions.
Nationwide, >90% of patients with commercial coverage have access to ZEPOSIAe
Find ZEPOSIA Coverage in Your Area
Step 1: Find ZEPOSIA coverage by location
In your area, of patients with commercial coverage have access to ZEPOSIA
Step 2: Filter results by health plan/pharmacy benefit manager (PBM) type



Find ZEPOSIA coverage by health plan/PBM
eBased on Weekly Field Intelligence Input and MMIT, as of August 2022.
For most payers, prior authorization requirements include confirmation of diagnosis, prescribed by a specialist, and previous failure of generic therapies. However, different or additional criteria may apply. Please contact ZEPOSIA 360 SupportTM for assistance.
Resource Downloads
Patient Resources
Start Form
Enrolls patients in ZEPOSIA 360 Support and helps them get started on treatment. Download the start form or get started online.
BMS eSign
Available for your patients who forget to sign the ZEPOSIA Start Form. BMS eSign enables your patients to sign electronically via CoverMyMeds.
Initiation and Support Brochure
Provides important information on how to get patients started on ZEPOSIA and an overview of key benefits available through the ZEPOSIA 360 Support program.
Tyramine and ZEPOSIA Food and Drug Interaction Information
A helpful list of food and beverages that are high in tyramine (150 mg or more)—a compound that should be avoided at high levels if your patients are taking ZEPOSIA.
Patient Decision Kit
Provides a comprehensive look at ZEPOSIA for patients and outlines steps to get them started on therapy.
Patient Brochure
Provides a streamlined version of the Patient Decision Kit, including a quick overview of ZEPOSIA and ZEPOSIA 360 Support.
Baseline Assessment Assistance Brochure
Outlines the process for in-home or in-office baseline assessment testing assistance for eligible patients enrolled in ZEPOSIA 360 Support.
ZEPOSIA 360 Patient Journey
Outlines support available for patients who are enrolled in ZEPOSIA 360 Support.
Access & Support
Authorization and Appeals Kit
Offers information on potential coverage scenarios for ZEPOSIA, and outlines services offered by ZEPOSIA 360 Support.
Formulary Exception Letter
Helps you advocate for your patients, so
they can gain approval to start therapy
with ZEPOSIA.
Letter for Medical Necessity for Patients Currently Receiving MS Treatment
Enables you to help your patients continue receiving therapy.
Letter for Medical Necessity for Patients Not Currently Receiving MS Treatment
Helps your patients not currently receiving any therapy to get started on ZEPOSIA.
Letter of Appeal for Patients Currently Receiving MS Treatment
Enables you to advocate for patients who are currently receiving therapy, if they receive an unfavorable coverage decision.
Letter of Appeal for Patients Not Currently Receiving MS Treatment
Enables you to advocate for patients who are not currently receiving therapy, if they receive an unfavorable coverage decision.
Step Therapy Letter
Helps you advocate for your patients if step requirements apply, so they can gain approval to start or continue prescribed therapy with ZEPOSIA.
Additional Resources
Specialty Pharmacy Resource
Provides a quick overview of the benefits of using Specialty Pharmacies (SPs) and a list of SPs ready to handle ZEPOSIA prescriptions.
Baseline Testing Completion Form
This form is used by the ZEPOSIA 360 Support clinical partners to verify that a patient’s baseline tests have been reviewed by their prescriber and that they are able to start therapy. This form needs to be submitted, either online or by fax. If not, someone from ZEPOSIA 360 Support will contact you for verbal confirmation of baseline test completion.
Patient Profile – DMT Naive
Meet Emily, a newly diagnosed RMS patient looking for her first DMT. Not an actual patient.
Learn More From a Leading Expert
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Watch Video: Learn from Leading Expert Douglas Stuart, MD Watch Video: Learn from Leading Expert Douglas Stuart, MD
Douglas Stuart, MD
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